Home 2018 - Volume 18 (2) PREDICTIVE MODELLING OF VISUAL ACUITY UPON DIABETIC RETINOPATHY IN TYPE 2 DIABETES MELLITUS
PREDICTIVE MODELLING OF VISUAL ACUITY UPON DIABETIC RETINOPATHY IN TYPE 2 DIABETES MELLITUS PDF Print E-mail
Saturday, 19 January 2019 15:17

 

Xin Wee Chen1,2, Zaliha Ismail2,3, Embong Zunaina4 and Kamarul Imran Musa1

1Department of Community Medicine, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

2Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia.

3Institute of Pathology, Laboratory and Forensic Medicine (I-PPerForM), Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia.

4Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Corresponding author: Xin Wee Chen

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ABSTRACT

The worldwide upsurge of Type 2 Diabetes Mellitus (T2DM) warrants the attention of public health, especially in complications. Diabetic Retinopathy (DR), the commonest ocular complication, contributes to the growing incidence of blindness. Recommendations that the visual acuity (VA) assessment guidelines should be used in DR screening was not routinely practiced. This study aims to model the predictive effect of VA - a simple economic clinical assessment - upon DR in patients with T2DM. A case-control study was conducted in Hospital Universiti Sains Malaysia with subjects recruited from the ophthalmology clinic. The primary variable during analysis was VA, and the outcome variable was DR. Models with eight control variables which included age, gender, and duration of DM were developed. The predictive effect measured by logistic regression showed that when unadjusted; four variables had a significant association with DR, at p-value<0.25; they were the duration of DM, systolic blood pressure, glycosylated haemoglobin and VA. From the eight different predictive models, the estimated adjusted odds ratio produced ranges from 6.09 to 11.64. Our study shows that VA has a predictive effect upon DR in T2DM patients. We suggest VA assessment,  to be on par with the monitoring of blood pressure and blood glucose.

Keywords: Predictive, Visual acuity, Diabetic Retinopathy, Type 2 Diabetes Mellitus.

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Last Updated on Saturday, 19 January 2019 15:21
 

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ISSN No : 1675-0306
e-ISSN No : 2590-3829

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