Home 2017 - Volume 17 (1) SOYBEAN, CASSAVA AND CABBAGE LOCALLY GROWN IN A IODINE DEFICIENT AREA IN CENTRAL JAVA ARE GOITROGENIC TO RATS
SOYBEAN, CASSAVA AND CABBAGE LOCALLY GROWN IN A IODINE DEFICIENT AREA IN CENTRAL JAVA ARE GOITROGENIC TO RATS PDF Print E-mail
Saturday, 06 May 2017 17:46

Yulia Lanti Retno Dewi,1 Widardo2 and Bambang Suprapto2

1 Department of Biology, School of Medicine Sebelas Maret University, Indonesia, Jl. Ir. Sutami 36 A Surakarta 57126.

2 Department of Nutrition, School of Medicine Sebelas Maret University, Indonesia, Jl. Ir. Sutami 36 A Surakarta 57126.

ABSTRACT

Although the relation of iodine deficiency to endemic goiter is well established, other factors may be involved. Some factors are related to food. The aim of the study was to prove that some foods locally grown in an iodine deficient area are goitrogenic. Twenty eight Wistar rats age 28 days, weight 60-70 g were randomly assigned into seven groups. The first group fed with AIN-93G as control group. Group II and III were given 25% and 50% raw soybean replacing the same weight of AIN-93G. Group IV and V were given 25% and 50% raw cassava replacing the same weight of AIN-93G. Group VI and VII were given 25% % and 50% raw cabbage replacing the same weight of AIN-93G. The length of the experiment was 34 days. The results showed that the control group fed with AIN-93G grew optimally, while the other groups showed deficits in growth significantly. Histological preparation of the thyroid gland were carried out under hematoxilyn eosin staining. Both 25% and 50% of raw soybean, raw cassava and raw cabbage produced colloid goiter. The study proved that foods locally grown in an iodine deficient area are goitrogenic.

 

Keywords: goitrogen, soybean, cassava, cabbage.

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Last Updated on Monday, 08 May 2017 23:42
 

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ISSN No : 1675-0306
e-ISSN No : 2590-3829

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